Antinociceptive properties of 25-methoxy hispidol A, a triterpinoid isolated from Poncirus trifoliata (Rutaceae) through inhibition of NF-&#954;B signalling in mice.

Khan, Ashrafullah; Ullah, Muhammad Zia; Afridi, Ruqayya; Rasheed, Hina; Khalid, Sidra; Ullah, Hadayat; Ali, Hussain; AlSharari, Shakir D; Kim, Yeong Shik; Khan, Salman

Antinociceptive properties of 25-methoxy hispidol A, a triterpinoid isolated from Poncirus trifoliata (Rutaceae) through inhibition of NF-κB signalling in mice.

Khan, Ashrafullah; Ullah, Muhammad Zia; Afridi, Ruqayya; Rasheed, Hina; Khalid, Sidra; Ullah, Hadayat; Ali, Hussain; AlSharari, Shakir D; Kim, Yeong Shik; Khan, Salman.

Afiliación

Khan A; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Ullah MZ; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Afridi R; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Rasheed H; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Khalid S; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Ullah H; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Ali H; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
AlSharari SD; Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Kim YS; College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, South Korea.
Khan S; Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

Phytother Res ; 33(2): 327-341, 2019 Feb.

Article en En | MEDLINE | ID: mdl-30456885

Asunto(s)

Analgésicos/uso terapéutico; Hiperalgesia/tratamiento farmacológico; Dolor/tratamiento farmacológico; Poncirus/química; Triterpenos/uso terapéutico; Analgésicos/farmacología; Animales; Carragenina; Regulación hacia Abajo/efectos de los fármacos; Edema/inducido químicamente; Edema/tratamiento farmacológico; Adyuvante de Freund; Hiperalgesia/inducido químicamente; Hiperalgesia/metabolismo; Inflamación/tratamiento farmacológico; Inflamación/metabolismo; Masculino; Ratones; FN-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo II/metabolismo; Dolor/inducido químicamente; Dolor/metabolismo; Rutaceae/química; Transducción de Señal/efectos de los fármacos; Triterpenos/farmacología

Palabras clave

CFA; allodynia; carrageenan; cytokines; hyperalgesia; nociception

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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia / Plantas_medicinales Asunto principal: Dolor / Triterpenos / Poncirus / Hiperalgesia / Analgésicos Idioma: En Revista: Phytother Res Año: 2019 Tipo del documento: Article País de afiliación: Pakistán

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