HPLC-DAD-SPE-NMR isolation of tetracyclic spiro-alkaloids with antiplasmodial activity from the seeds of <i>Erythrina latissima</i>.

Zarev, Yancho; Foubert, Kenn; Cos, Paul; Maes, Louis; Elgorashi, Esameldin; Apers, Sandra; Ionkova, Iliana; Pieters, Luc

HPLC-DAD-SPE-NMR isolation of tetracyclic spiro-alkaloids with antiplasmodial activity from the seeds of Erythrina latissima.

Zarev, Yancho; Foubert, Kenn; Cos, Paul; Maes, Louis; Elgorashi, Esameldin; Apers, Sandra; Ionkova, Iliana; Pieters, Luc.

Afiliación

Zarev Y; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Foubert K; Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, Sofia, Bulgaria.
Cos P; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Elgorashi E; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Apers S; Toxicology and Ethnoveterinary Medicine; Food, Feed and Veterinary Public Health, ARC-Onderstepoort Veterinary Institute, Onderstepoort, South-Africa.
Ionkova I; Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Pieters L; Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, Sofia, Bulgaria.

Nat Prod Res ; 34(7): 1037-1040, 2020 Apr.

Article en En | MEDLINE | ID: mdl-30602319

Asunto(s)

Alcaloides/aislamiento & purificación; Alcaloides/farmacología; Antimaláricos/aislamiento & purificación; Erythrina/química; Extractos Vegetales/química; Alcaloides/química; Antimaláricos/química; Línea Celular; Cloroquina/farmacología; Cromatografía Líquida de Alta Presión; Dihidro-beta-Eritroidina/análogos & derivados; Resistencia a Medicamentos; Humanos; Alcaloides Indólicos; Espectroscopía de Resonancia Magnética; Extractos Vegetales/análisis; Extractos Vegetales/farmacología; Plasmodium falciparum/efectos de los fármacos; Semillas/química

Palabras clave

Erythrina alkaloids; Erythrina latissima; HPLC-DAD-SPE-NMR; antiplasmodial activity; cytotoxicity

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Extractos Vegetales / Alcaloides / Erythrina / Antimaláricos Idioma: En Revista: Nat Prod Res Año: 2020 Tipo del documento: Article País de afiliación: Bélgica

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