Biological activities and chemical components of Potentilla kleiniana Wight & Arn.
Nat Prod Res
; 34(22): 3262-3266, 2020 Nov.
Article
en En
| MEDLINE
| ID: mdl-30663365
ABSTRACT
In this study, we investigated the antimicrobial, antioxidant, and cytoprotective activities of ethanol extract and the ethyl acetate (EtOAc) fraction of P. kleiniana Wight & Arn. The EtOAc fraction exhibited antimicrobial effects against most of the microorganisms that were tested, including Staphylococcus aureus, Candida albicans, Pseudomonas aeruginosa, and, Escherichia coli, but not Aspergillus niger. In addition to its excellent antioxidant activity, the EtOAc fraction attenuated the UVB-induced cell death via upregulation of caspase-3 expression in human keratinocytes. The HPLC/ESI-MS/MS analysis allowed identification of the components in the EtOAc fraction. Overall, our results suggest that P. kleiniana is a valuable source of bioactive compounds for the development of pharmaceuticals and cosmetics.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
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Potentilla
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Antiinfecciosos
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Antioxidantes
Idioma:
En
Revista:
Nat Prod Res
Año:
2020
Tipo del documento:
Article
País de afiliación:
Corea del Sur