Rutin protects t­butyl hydroperoxide-induced oxidative impairment via modulating the Nrf2 and iNOS activity.

Singh, Shilpi; Singh, Dhananjay Kumar; Meena, Abha; Dubey, Vijaya; Masood, Nusrat; Luqman, Suaib

Rutin protects tbutyl hydroperoxide-induced oxidative impairment via modulating the Nrf2 and iNOS activity.

Singh, Shilpi; Singh, Dhananjay Kumar; Meena, Abha; Dubey, Vijaya; Masood, Nusrat; Luqman, Suaib.

Afiliación

Singh S; Molecular Bioprospection Department of Biotechnology Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India.
Singh DK; Molecular Bioprospection Department of Biotechnology Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India.
Meena A; Molecular Bioprospection Department of Biotechnology Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India.
Dubey V; Molecular Bioprospection Department of Biotechnology Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India.
Masood N; Molecular Bioprospection Department of Biotechnology Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India.
Luqman S; Molecular Bioprospection Department of Biotechnology Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India. Electronic address: s.luqman@cimap.res.in.

Phytomedicine ; 55: 92-104, 2019 Mar 01.

Article en En | MEDLINE | ID: mdl-30668448

Asunto(s)

Glucósidos/farmacología; Hígado/efectos de los fármacos; Factor 2 Relacionado con NF-E2/metabolismo; Óxido Nítrico Sintasa de Tipo II/metabolismo; Estrés Oxidativo/efectos de los fármacos; Quercetina/análogos & derivados; Rutina/farmacología; Animales; Antioxidantes/farmacología; Células Cultivadas; Femenino; Humanos; Hígado/metabolismo; Ratones; Quercetina/farmacología; Especies Reactivas de Oxígeno/metabolismo; Transducción de Señal/efectos de los fármacos; Regulación hacia Arriba/efectos de los fármacos; terc-Butilhidroperóxido/toxicidad

Palabras clave

Erythrocytes; Nrf2; Oxidative stress; Rutin; iNOS; t-BHP

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quercetina / Rutina / Estrés Oxidativo / Óxido Nítrico Sintasa de Tipo II / Factor 2 Relacionado con NF-E2 / Glucósidos / Hígado Idioma: En Revista: Phytomedicine Año: 2019 Tipo del documento: Article País de afiliación: India

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