Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage.
Analyst
; 144(11): 3488-3493, 2019 Jun 07.
Article
en En
| MEDLINE
| ID: mdl-30939183
ABSTRACT
The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (µg kg-1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Selenio
/
Cartílago Articular
Idioma:
En
Revista:
Analyst
Año:
2019
Tipo del documento:
Article
País de afiliación:
Reino Unido