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Sasanquasaponin ΙΙΙ from Schima crenata Korth induces autophagy through Akt/mTOR/p70S6K pathway and promotes apoptosis in human melanoma A375 cells.
Liang, Qiu-Ping; Xu, Tian-Qi; Liu, Bai-Lian; Lei, Xue-Ping; Hambrook, Jacob R; Zhang, Dong-Mei; Zhou, Guang-Xiong.
Afiliación
  • Liang QP; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Product, College of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, China.
  • Xu TQ; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Product, College of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, China.
  • Liu BL; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Product, College of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, China.
  • Lei XP; College of Pharmacy, Guangzhou Medical University, Guangzhou, Guangdong 510632, China.
  • Hambrook JR; School of Public Health, University of Alberta, Edmonton, AB T6G2G7, Canada.
  • Zhang DM; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Product, College of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, China.
  • Zhou GX; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Product, College of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, China. Electronic address: guangxzh@sina.com.
Phytomedicine ; 58: 152769, 2019 May.
Article en En | MEDLINE | ID: mdl-31005714
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Saponinas / Autofagia / Apoptosis / Theaceae / Melanoma / Antineoplásicos Idioma: En Revista: Phytomedicine Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Saponinas / Autofagia / Apoptosis / Theaceae / Melanoma / Antineoplásicos Idioma: En Revista: Phytomedicine Año: 2019 Tipo del documento: Article País de afiliación: China