Dalestones A and B, two anti-inflammatory cyclopentenones from Daldinia eschscholzii with an edited strong promoter for the global regulator LaeA-like gene.

Zhou, Zhen-Zhen; Zhu, Hong-Jie; Yang, Cheng-Long; Liu, Yan-Jun; Jiang, Nan; Xiao, Yong-Sheng; Shi, Li-Yun; Jiao, Rui-Hua; Ge, Hui-Ming; Tan, Ren-Xiang

Zhou, Zhen-Zhen; Zhu, Hong-Jie; Yang, Cheng-Long; Liu, Yan-Jun; Jiang, Nan; Xiao, Yong-Sheng; Shi, Li-Yun; Jiao, Rui-Hua; Ge, Hui-Ming; Tan, Ren-Xiang.

Afiliación

Zhou ZZ; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Nanjing University, Nanjing 210023, China.
Zhu HJ; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Nanjing University, Nanjing 210023, China.
Yang CL; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Nanjing University, Nanjing 210023, China.
Liu YJ; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jiang N; School of Pharmacy, Nanjing Medical University, Nanjing, 210029, China.
Xiao YS; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Nanjing University, Nanjing 210023, China.
Shi LY; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jiao RH; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Nanjing University, Nanjing 210023, China.
Ge HM; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Nanjing University, Nanjing 210023, China. Electronic address: hmge@nju.edu.cn.
Tan RX; State Key Laboratory of Pharmaceutical Biotechnology, Institute of Functional Biomolecules, Nanjing University, Nanjing 210023, China; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address: rxtan@nju.edu.

Chin J Nat Med ; 17(5): 387-393, 2019 May 20.

Article en En | MEDLINE | ID: mdl-31171274

Asunto(s)

Antiinflamatorios/farmacología; Ciclopentanos/farmacología; Proteínas Fúngicas/genética; Regiones Promotoras Genéticas/genética; Factores de Transcripción/genética; Xylariales/química; Animales; Antiinflamatorios/química; Antiinflamatorios/aislamiento & purificación; Antiinflamatorios/metabolismo; Ciclopentanos/química; Ciclopentanos/aislamiento & purificación; Ciclopentanos/metabolismo; Proteínas Fúngicas/metabolismo; Interleucina-6/metabolismo; Lipopolisacáridos/farmacología; Macrófagos/efectos de los fármacos; Macrófagos/metabolismo; Ratones; Estructura Molecular; Células RAW 264.7; Factores de Transcripción/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo; Xylariales/genética; Xylariales/metabolismo

Palabras clave

Cyclopentenone; Daldinia eschscholzii; Global regulator

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Xylariales / Factores de Transcripción / Proteínas Fúngicas / Regiones Promotoras Genéticas / Ciclopentanos / Antiinflamatorios Idioma: En Revista: Chin J Nat Med Año: 2019 Tipo del documento: Article País de afiliación: China

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