Bioinspired synthesis and characterization of gold nano-particles from medicinally important Periploca hydaspidis and their in vitro antioxidant and antimicrobial activity.
Pak J Pharm Sci
; 32(3): 1069-1080, 2019 May.
Article
en En
| MEDLINE
| ID: mdl-31278722
ABSTRACT
This research investigates the synthesis and characterization of gold nanoparticles from Periploca hydaspidis and their antimicrobial and anti oxidant activity. The synthesis of AuNPs was confirmed by UV-Vis spectrophotometer and structure by a high resolution atomic force microscope. X-ray diffraction and Fourier transformed infrared spectroscopy was used to study the crystallite size and different functional groups. DPPH radical scavenging activity and disc diffusion protocol was applied for the determination of antioxidant and antimicrobial activity. A ratio of 18 of 1mM AuCl3 solutions with plant boiled extract used for synthesis of gold nano-particles. The formation of the gold nano-particles was determined by the color change from yellow to dark purple which were confirmed by UV-Vis spectrophotometer. Gold nano-particles were stable between 24°C and 39°C, mM concentration of the salt and neutral pH. The groups responsible for the synthesis of gold nano-paricles were Alkenes and aliphatic amines. The AuNP were cubic in nature and the nanocrystallite size was 6.99nm. Gold nano-particles revealed good antioxidant activity and controlled the growth of K. pnemoniae, E. coli, X. compestris, C. albicans and P. chrysogenum.
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Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
Asunto principal:
Periploca
/
Nanopartículas del Metal
/
Antiinfecciosos
/
Antioxidantes
Idioma:
En
Revista:
Pak J Pharm Sci
Año:
2019
Tipo del documento:
Article
País de afiliación:
Pakistán