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New butenolides with anti-inflammatory activity from Balanophora fungosa.
Zhou, Jie; Du, Si-Yu; Fang, Zhong-Ying; Zeng, Zhi.
Afiliación
  • Zhou J; School of Biological Science and Technology, University of Jinan, Jinan, China.
  • Du SY; Key laboratory of Natural Pharmaceutical Chemistry, Shandong University of Traditional Chinese Medicine, Jinan, China.
  • Fang ZY; Key laboratory of Natural Pharmaceutical Chemistry, Shandong University of Traditional Chinese Medicine, Jinan, China.
  • Zeng Z; Reproductive Medicine Center, The Sixth affiliated hospital of Sun Yat-sen University, Guangzhou, China.
Nat Prod Res ; 35(11): 1825-1829, 2021 Jun.
Article en En | MEDLINE | ID: mdl-31359786
Two new butenolides, balanolides A (1) and B (1), were isolated from the aerial parts of the parasitic plant Balanophora fungosa. Their structures were established by comprehensive spectroscopic analysis and quantum chemical ECD calculation. The new butenolides were evaluated for their inhibitory effects against nitric oxide (NO) production in LPS-induced RAW 264.7 macrophage cells. Compounds 1 and 2 displayed moderate anti-inflammatory activity with IC50values of 11.8 and 12.9 µM, respectively.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: 4-Butirolactona / Balanophoraceae / Antiinflamatorios Idioma: En Revista: Nat Prod Res Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: 4-Butirolactona / Balanophoraceae / Antiinflamatorios Idioma: En Revista: Nat Prod Res Año: 2021 Tipo del documento: Article País de afiliación: China