Tanshinone IIA attenuates demyelination and promotes remyelination in <i>A. cantonensis</i>-infected BALB/c mice.

Feng, Ying; Feng, Feng; Zheng, Cunjing; Zhou, Zongpu; Jiang, Meihua; Liu, Zhen; Xie, Fukang; Sun, Xi; Wu, Zhongdao

Tanshinone IIA attenuates demyelination and promotes remyelination in A. cantonensis-infected BALB/c mice.

Feng, Ying; Feng, Feng; Zheng, Cunjing; Zhou, Zongpu; Jiang, Meihua; Liu, Zhen; Xie, Fukang; Sun, Xi; Wu, Zhongdao.

Afiliación

Feng Y; Medical School of South China University of Technology, Guangzhou, China.
Feng F; The Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Zheng C; Histology and Embryology Department of Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Zhou Z; Medical School of South China University of Technology, Guangzhou, China.
Jiang M; Anatomy Department of Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Liu Z; Guangzhou First People's Hospital, Guangzhou, China.
Xie F; Histology and Embryology Department of Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Sun X; Parasitology Department of Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Wu Z; Key Laboratory of Tropical Disease Control (SYSU), Ministry of Education, Guangzhou, China.

Int J Biol Sci ; 15(10): 2211-2223, 2019.

Article en En | MEDLINE | ID: mdl-31592236

Asunto(s)

Abietanos/uso terapéutico; Angiostrongylus cantonensis/efectos de los fármacos; Angiostrongylus cantonensis/patogenicidad; Infecciones por Strongylida/tratamiento farmacológico; Albendazol/farmacología; Animales; Western Blotting; Enfermedades Desmielinizantes/tratamiento farmacológico; Técnica del Anticuerpo Fluorescente; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Ratones; Ratones Endogámicos BALB C; Microscopía Electrónica de Transmisión; Vaina de Mielina/efectos de los fármacos; Óxido Nítrico Sintasa de Tipo II/metabolismo; Remielinización/efectos de los fármacos; Infecciones por Strongylida/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

A. cantonensis; Tanshinone IIA; demyelination; microglia polarization; remyelination

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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Infecciones por Strongylida / Angiostrongylus cantonensis / Abietanos Idioma: En Revista: Int J Biol Sci Año: 2019 Tipo del documento: Article País de afiliación: China

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