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Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration.
Panchaud, Philippe; Surivet, Jean-Philippe; Diethelm, Stefan; Blumstein, Anne-Catherine; Gauvin, Jean-Christophe; Jacob, Loïc; Masse, Florence; Mathieu, Gaëlle; Mirre, Azely; Schmitt, Christine; Enderlin-Paput, Michel; Lange, Roland; Gnerre, Carmela; Seeland, Swen; Herrmann, Charlyse; Locher, Hans H; Seiler, Peter; Ritz, Daniel; Rueedi, Georg.
Afiliación
  • Panchaud P; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Surivet JP; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Diethelm S; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Blumstein AC; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Gauvin JC; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Jacob L; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Masse F; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Mathieu G; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Mirre A; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Schmitt C; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Enderlin-Paput M; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Lange R; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Gnerre C; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Seeland S; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Herrmann C; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Locher HH; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Seiler P; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Ritz D; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
  • Rueedi G; Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91 , CH-4123 Allschwil , Switzerland.
J Med Chem ; 63(1): 88-102, 2020 01 09.
Article en En | MEDLINE | ID: mdl-31804829
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Plantas_medicinales Asunto principal: Inhibidores Enzimáticos / Infecciones por Escherichia coli / Amidohidrolasas / Ácidos Hidroxámicos / Antibacterianos Idioma: En Revista: J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: Suiza
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Plantas_medicinales Asunto principal: Inhibidores Enzimáticos / Infecciones por Escherichia coli / Amidohidrolasas / Ácidos Hidroxámicos / Antibacterianos Idioma: En Revista: J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: Suiza