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"Whole" vs. "fragmented" approach to EAACI pollen season definitions: A multicenter study in six Southern European cities.
Hoffmann, Tara Maria; Acar Sahin, Aydan; Aggelidis, Xenophon; Arasi, Stefania; Barbalace, Andrea; Bourgoin, Anne; Bregu, Blerina; Brighetti, Maria Antonia; Caeiro, Elsa; Caglayan Sozmen, Sule; Caminiti, Lucia; Charpin, Denis; Couto, Mariana; Delgado, Luís; Di Rienzo Businco, Andrea; Dimier, Claire; Dimou, Maria V; Fonseca, João A; Goksel, Ozlem; Guvensen, Aykut; Hernandez, Dolores; Jang, Dah Tay; Kalpaklioglu, Fusun; Lame, Blerta; Llusar, Ruth; Makris, Michael P; Mazon, Angel; Mesonjesi, Eris; Nieto, Antonio; Öztürk, Ayse; Pahus, Laurie; Pajno, Giovanni Battista; Panasiti, Ilenia; Panetta, Valentina; Papadopoulos, Nikolaos G; Pellegrini, Elisabetta; Pelosi, Simone; Pereira, Ana Margarida; Pereira, Mariana; Pinar, Munevver; Pfaar, Oliver; Potapova, Ekaterina; Priftanji, Alfred; Psarros, Fotis; Sackesen, Cansin; Sfika, Ifigenia; Suarez, Javier; Thibaudon, Michel; Travaglini, Alessandro; Tripodi, Salvatore.
Afiliación
  • Hoffmann TM; Department of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
  • Acar Sahin A; Department of Biology, Faculty of Science, Ankara University, Ankara, Turkey.
  • Aggelidis X; Allergy Unit, 2nd Department of Dermatology and Venereology, National and Kapodistrian University of Athens, University Hospital "Attikon", Athens, Greece.
  • Arasi S; Pediatric Allergology Unit, Department of Pediatric Medicine, Bambino Gesù Children´s research Hospital (IRCCS), Rome, Italy.
  • Barbalace A; Department of Pediatrics- Allergy Unit, University of Messina, Messina, Italy.
  • Bourgoin A; Department of Pneumonology and Allergy, La Timone Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Bregu B; Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Brighetti MA; Department of Allergology and Clinical Immunology, UHC Mother Teresa, Medical University Tirana, Tirana, Albania.
  • Caeiro E; Department of Biology, Tor Vergata University, Rome, Italy.
  • Caglayan Sozmen S; MED - Mediterranean Institute for Agriculture, Environment and Development, Institute for Advanced Studies and Research, University of Évora, Évora, Portugal.
  • Caminiti L; Portuguese Society of Allergology and Clinical Immunology, Lisbon, Portugal.
  • Charpin D; Department of Pediatric Allergy and Immunology, Okan University Faculty of Medicine, Istanbul, Turkey.
  • Couto M; Department of Pediatrics- Allergy Unit, University of Messina, Messina, Italy.
  • Delgado L; Department of Pneumonology and Allergy, La Timone Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Di Rienzo Businco A; Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Dimier C; Immunoallergology, José de Mello Saúde, Porto, Portugal.
  • Dimou MV; Basic and Clinical Immunology Unit, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal.
  • Fonseca JA; CINTESIS, Center for Health Technology and Services Research, Bologna, Portugal.
  • Goksel O; Allergy Unit, Instituto & Hospital CUF Porto, Porto, Portugal.
  • Guvensen A; Pediatric Allergy Unit, Sandro Pertini Hospital, Rome, Italy.
  • Hernandez D; Department of Pneumonology and Allergy, La Timone Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Jang DT; Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Kalpaklioglu F; Allergy Department, 2nd Pediatric Clinic, Athens General Children's Hospital "P&A Kyriakou", University of Athens, Athens, Greece.
  • Lame B; CINTESIS, Center for Health Technology and Services Research, Bologna, Portugal.
  • Llusar R; Allergy Unit, Instituto & Hospital CUF Porto, Porto, Portugal.
  • Makris MP; MEDCIDS-Department of Community Medicine, Information, and Health Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
  • Mazon A; Department of Pulmonary Medicine, Division of Immunology, Allergy and Asthma, Faculty of Medicine, Ege University, Izmir, Turkey.
  • Mesonjesi E; Department of Biology, Faculty of Science, Ege University, Izmir, Turkey.
  • Nieto A; Service of Allergy, Hospital La Fe; Health Research Institute La Fe, Valencia, Spain.
  • Öztürk A; Pediatric Allergy and Pneumology Unit, Children's Hospital La Fe; Health Research Institute La Fe, Valencia, Spain.
  • Pahus L; Department of Chest Diseases, Division of Immunology and Allergic Diseases, Kirikkale University School of Medicine, Kirikkale, Turkey.
  • Pajno GB; Department of Allergology and Clinical Immunology, UHC Mother Teresa, Medical University Tirana, Tirana, Albania.
  • Panasiti I; Pediatric Allergy and Pneumology Unit, Children's Hospital La Fe; Health Research Institute La Fe, Valencia, Spain.
  • Panetta V; Allergy Unit, 2nd Department of Dermatology and Venereology, National and Kapodistrian University of Athens, University Hospital "Attikon", Athens, Greece.
  • Papadopoulos NG; Pediatric Allergy and Pneumology Unit, Children's Hospital La Fe; Health Research Institute La Fe, Valencia, Spain.
  • Pellegrini E; Department of Allergology and Clinical Immunology, UHC Mother Teresa, Medical University Tirana, Tirana, Albania.
  • Pelosi S; Pediatric Allergy and Pneumology Unit, Children's Hospital La Fe; Health Research Institute La Fe, Valencia, Spain.
  • Pereira AM; Department of Allergy and Immunology, Koç University Hospital, Istanbul, Turkey.
  • Pereira M; Department of Pneumonology and Allergy, La Timone Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Pinar M; Hospital, APHM, Aix-Marseille University, Marseille, France.
  • Pfaar O; Department of Pediatrics- Allergy Unit, University of Messina, Messina, Italy.
  • Potapova E; Department of Pediatrics- Allergy Unit, University of Messina, Messina, Italy.
  • Priftanji A; Biostatistics, L'altrastatistica srl, Consultancy & Training, Rome, Italy.
  • Psarros F; Division of Infection, Immunity& Respiratory Medicine, Royal Manchester Children's Hospital, University of Manchester, Manchester, UK.
  • Sackesen C; MEDCIDS-Department of Community Medicine, Information, and Health Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
  • Sfika I; Biostatistics, L'altrastatistica srl, Consultancy & Training, Rome, Italy.
  • Suarez J; Division of Infection, Immunity& Respiratory Medicine, Royal Manchester Children's Hospital, University of Manchester, Manchester, UK.
  • Thibaudon M; Department of Reggio Calabria, ARPACal- Regional Agency for Environmental Protection, Messina, Italy.
  • Travaglini A; TPS Production srl, Rome, Italy.
  • Tripodi S; CINTESIS, Center for Health Technology and Services Research, Bologna, Portugal.
Allergy ; 75(7): 1659-1671, 2020 07.
Article en En | MEDLINE | ID: mdl-31833579
BACKGROUND: The adequate definition of pollen seasons is essential to facilitate a correct diagnosis, treatment choice, and outcome assessment in patients with seasonal allergic rhinitis. A position paper by the European Academy of Allergy and Clinical Immunology (EAACI) proposed season definitions for Northern and Middle Europe. OBJECTIVE: To test the pollen season definitions proposed by EAACI in six Mediterranean cities for seven pollen taxa. METHODS: As part of the @IT.2020 multi-center study, pollen counts for Poaceae, Oleaceae, Fagales, Cupressaceae, Urticaceae (Parietaria spp.), and Compositae (Ambrosia spp., Artemisia spp.) were collected from January 1 to December 31, 2018. Based on these data, pollen seasons were identified according to EAACI criteria. A unified monitoring period for patients in AIT trials was created and assessed for feasibility. RESULTS: The analysis revealed a great heterogeneity between the different locations in terms of pattern and length of the examined pollen seasons. Further, we found a fragmentation of pollen seasons in several segments (max. 8) separated by periods of low pollen counts (intercurrent periods). Potential monitoring periods included often many recording days with low pollen exposure (max. 341 days). CONCLUSION: The Mediterranean climate leads to challenging pollen exposure times. Monitoring periods for AIT trials based on existing definitions may include many intermittent days with low pollen concentrations. Therefore, it is necessary to find an adapted pollen season definition as individual solution for each pollen and geographical area.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polen / Rinitis Alérgica Estacional Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies País/Región como asunto: Europa Idioma: En Revista: Allergy Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Añadir a Mi BVS
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polen / Rinitis Alérgica Estacional Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies País/Región como asunto: Europa Idioma: En Revista: Allergy Año: 2020 Tipo del documento: Article País de afiliación: Alemania