Ilex paraguariensis, white mulberry and chromium picolinate in patients with pre-diabetes.
Phytother Res
; 34(6): 1377-1384, 2020 Jun.
Article
en En
| MEDLINE
| ID: mdl-31994278
ABSTRACT
AIM:
to evaluate if a nutraceutical compound containing Ilex paraguariensis, White Mulberry and Chromium Picolinate can ameliorate glycemic status in patients with pre-diabetes.METHODS:
we enrolled patients with IFG or IGT, not taking other hypoglycemic compounds. Patients were randomized to take placebo or the nutraceutical compound for 3 months, in a randomized, double-blind, placebo-controlled design. Both treatments were self-administered once a day, 1 tablet during the breakfast.RESULTS:
a reduction of FPG was observed with the nutraceutical combination (-7.8%). Furthermore, there was a decrease of HOMA-IR with the nutraceutical combination (-7.9%). M value was higher (p < 0.05 vs baseline and p < 0.05 vs placebo) at the end of the treatment. We obtained a reduction of Tg with the nutraceutical combination (-8.3%). About 16.6% of patients treated with nutraceutical returned to have a normal glycemia (< 100 mg/dL), and all patients had an improvement of insulin-resistance, in particular 67% of patients returned to have a M value inside range of normal insulin sensitivity.CONCLUSIONS:
a nutraceutical containing Ilex paraguariensis, White Mulberry and Chromium Picolinate at 500 mg can be helpful in improving glycemia and Tg value, in patients with pre-diabetes.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Ácidos Picolínicos
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Estado Prediabético
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Glucemia
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Ilex paraguariensis
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Morus
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Hipoglucemiantes
Tipo de estudio:
Clinical_trials
Idioma:
En
Revista:
Phytother Res
Año:
2020
Tipo del documento:
Article
País de afiliación:
Italia