Methods for the Analysis of Polyphosphate in the Life Sciences.
Anal Chem
; 92(6): 4167-4176, 2020 03 17.
Article
en En
| MEDLINE
| ID: mdl-32039586
Inorganic polyphosphate (polyP) is the polymer of orthophosphate and can be found in all living organisms. For polyP characterization, one or more of six parameters are of interest: the molecular structure (linear, cyclic, or branched), the concentration, the average chain length, the chain length distribution, the cellular localization, and the cation composition. Here, the merits, limitations, and critical parameters of the state-of-the-art methods for the analysis of the six parameters from the life sciences are discussed. With this contribution, we aim to lower the entry barrier into the analytics of polyP, a molecule with prominent, yet often incompletely understood, contributions to cellular function.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Polifosfatos
/
Disciplinas de las Ciencias Biológicas
Idioma:
En
Revista:
Anal Chem
Año:
2020
Tipo del documento:
Article
País de afiliación:
Alemania