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New meroterpenoid compounds from the culture of mushroom Panus lecomtei.
Wang, Si-Xian; Zhao, Rui-Lin; Guo, Cui; Chen, Bao-Song; Dai, Huan-Qin; Liu, Gao-Qiang; Liu, Hong-Wei.
Afiliación
  • Wang SX; Hunan Provincial Key Laboratory of Forestry Biotechnology & International Cooperation Base of Science and Technology Innovation on Forest Resource Biotechnology, Central South University of Forestry & Technology, Changsha 410004, China; State Key Laboratory of Mycology, Institute of Microbio
  • Zhao RL; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Savaid Medicine School, University of Chinese Academy of Sciences, Beijing 100049, China.
  • Guo C; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Savaid Medicine School, University of Chinese Academy of Sciences, Beijing 100049, China.
  • Chen BS; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Savaid Medicine School, University of Chinese Academy of Sciences, Beijing 100049, China.
  • Dai HQ; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Savaid Medicine School, University of Chinese Academy of Sciences, Beijing 100049, China.
  • Liu GQ; Hunan Provincial Key Laboratory of Forestry Biotechnology & International Cooperation Base of Science and Technology Innovation on Forest Resource Biotechnology, Central South University of Forestry & Technology, Changsha 410004, China. Electronic address: gaoliuedu@csuft.edu.cn.
  • Liu HW; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Savaid Medicine School, University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: liuhw@im.ac.cn.
Chin J Nat Med ; 18(4): 268-272, 2020 Apr.
Article en En | MEDLINE | ID: mdl-32402403
ABSTRACT
Two new meroterpenoid compounds (1 and 2) together with five known meroterpenoid derivatives (3-7) were isolated from solid culture of mushroom Panus lecomtei. The structures of new compounds were confirmed by the analysis of NMR and HR-ESI-MS spectroscopic data. The biosynthetic pathway of 1-7 was postulated. All isolated compounds were evaluated for antibacterial activities against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa and Bacillus Calmette-Guérin. Compound 3 exhibited weak antibacterial activity against Bacillus Calmette-Guérin with the inhibition rate of 83.6% at 100 µmol·L-1. Other compounds showed no antibacterial activities against all tested pathogens at 100 µmol·L-1.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Terpenos / Bacterias / Extractos Vegetales / Polyporales / Antibacterianos País/Región como asunto: Asia Idioma: En Revista: Chin J Nat Med Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Terpenos / Bacterias / Extractos Vegetales / Polyporales / Antibacterianos País/Región como asunto: Asia Idioma: En Revista: Chin J Nat Med Año: 2020 Tipo del documento: Article