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Static Model-Based Assessment of OATP1B1-Mediated Drug Interactions with Preincubation-Dependent Inhibitors Based on Inactivation and Recovery Kinetics.
Taguchi, Takayuki; Masuo, Yusuke; Futatsugi, Azusa; Kato, Yukio.
Afiliación
  • Taguchi T; Pharmacokinetics and Safety Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., Kyoto, Japan (T.T.) and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan (T.T., Y.M., A.F., Y.K.).
  • Masuo Y; Pharmacokinetics and Safety Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., Kyoto, Japan (T.T.) and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan (T.T., Y.M., A.F., Y.K.).
  • Futatsugi A; Pharmacokinetics and Safety Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., Kyoto, Japan (T.T.) and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan (T.T., Y.M., A.F., Y.K.).
  • Kato Y; Pharmacokinetics and Safety Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., Kyoto, Japan (T.T.) and Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan (T.T., Y.M., A.F., Y.K.) ykato@p.kanazawa-u.ac.jp.
Drug Metab Dispos ; 48(9): 750-758, 2020 09.
Article en En | MEDLINE | ID: mdl-32616544
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transportador 1 de Anión Orgánico Específico del Hígado / Interacciones Farmacológicas / Eliminación Hepatobiliar / Modelos Biológicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Drug Metab Dispos Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transportador 1 de Anión Orgánico Específico del Hígado / Interacciones Farmacológicas / Eliminación Hepatobiliar / Modelos Biológicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Drug Metab Dispos Año: 2020 Tipo del documento: Article