Comprehensive Characterization of Secondary Metabolites from <i>Colebrookea oppositifolia</i> (Smith) Leaves from Nepal and Assessment of Cytotoxic Effect and Anti-Nf-&#954;B and AP-1 Activities In Vitro.

Peron, Gregorio; Hosek, Jan; Prasad Phuyal, Ganga; Raj Kandel, Dharma; Adhikari, Rameshwar; Dall'Acqua, Stefano

Comprehensive Characterization of Secondary Metabolites from Colebrookea oppositifolia (Smith) Leaves from Nepal and Assessment of Cytotoxic Effect and Anti-Nf-κB and AP-1 Activities In Vitro.

Peron, Gregorio; Hosek, Jan; Prasad Phuyal, Ganga; Raj Kandel, Dharma; Adhikari, Rameshwar; Dall'Acqua, Stefano.

Afiliación

Peron G; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy.
Hosek J; Division of Biologically Active Complexes and Molecular Magnets, Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacký University in Olomouc, Slechtitelu 27, 78371 Olomouc, Czech Republic.
Prasad Phuyal G; Research Centre for Applied Science and Technology, Tribhuvan University, Kiritipur, 44613 Kathmandu, Nepal.
Raj Kandel D; Research Centre for Applied Science and Technology, Tribhuvan University, Kiritipur, 44613 Kathmandu, Nepal.
Adhikari R; Research Centre for Applied Science and Technology, Tribhuvan University, Kiritipur, 44613 Kathmandu, Nepal.
Dall'Acqua S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy.

Int J Mol Sci ; 21(14)2020 Jul 11.

Article en En | MEDLINE | ID: mdl-32664524

Asunto(s)

Antiinflamatorios/farmacología; Lamiaceae/metabolismo; FN-kappa B/antagonistas & inhibidores; Extractos Vegetales/farmacología; Plantas Medicinales/metabolismo; Factor de Transcripción AP-1/antagonistas & inhibidores; Antiinflamatorios/aislamiento & purificación; Antiinflamatorios/toxicidad; Cromatografía Liquida; Flavonoides/análisis; Flavonoides/aislamiento & purificación; Humanos; Hidroxibenzoatos/análisis; Hidroxibenzoatos/aislamiento & purificación; Espectrometría de Masas; Metaboloma; Metanol; Nepal; Extractos Vegetales/química; Extractos Vegetales/aislamiento & purificación; Extractos Vegetales/toxicidad; Hojas de la Planta/metabolismo; Células THP-1

Palabras clave

Colebrookea oppositifolia; anti-AP-1; anti-NF-κB; cytotoxic activity; secondary metabolites

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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas Asunto principal: Plantas Medicinales / Extractos Vegetales / FN-kappa B / Factor de Transcripción AP-1 / Lamiaceae / Antiinflamatorios Tipo de estudio: Prognostic_studies País/Región como asunto: Asia Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Italia

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