Dietary Selenium Intakes and Musculoskeletal Function in Very Old Adults: Analysis of the Newcastle 85+ Study.
Nutrients
; 12(7)2020 Jul 12.
Article
en En
| MEDLINE
| ID: mdl-32664662
ABSTRACT
Background:
Selenium is a trace element essential for health. Severe selenium deficiencies are associated with poor musculoskeletal (MSK) function. However, the effects of moderate deficiency on MSK function, especially in older adults, is unclear.Objectives:
To determine the associations between selenium intake and MSK function in very old adults.Methods:
Selenium intake at baseline and, hand-grip strength (HGS) and timed-up-and-go (TUG) at four phases over 5 years, were available in 791 participants in the Newcastle 85+ Study, a community-based, longitudinal cohort of ≥85 year old individuals. We investigated relationships between selenium intake and HGS and TUG in cross-sectional analyses at baseline using multivariate analyses and, prospectively using linear mixed models to explore HGS and TUG changes over 5 years in association with baseline selenium intake.Results:
At baseline, 53% of participants had selenium intakes that were classified as low. These individuals had 2.80 kg lower HGS and were 2.30 s slower performing the TUG, cross-sectionally. In multivariate, baseline analyses, selenium intake had no significant impact on HGS or TUG. Selenium intake had no significant effect on MSK function, prospectively.Conclusion:
Low selenium intake is common among very old adults and, in cross-sectional analyses, is associated with poorer MSK function.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Selenio
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Envejecimiento
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Músculo Esquelético
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Fuerza de la Mano
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Ingestión de Alimentos
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Fenómenos Fisiológicos Nutricionales del Anciano
Tipo de estudio:
Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Nutrients
Año:
2020
Tipo del documento:
Article
País de afiliación:
Reino Unido