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An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Yao, Yao; Kadam, Rameshwar U; Lee, Chang-Chun David; Woehl, Jordan L; Wu, Nicholas C; Zhu, Xueyong; Kitamura, Seiya; Wilson, Ian A; Wolan, Dennis W.
Afiliación
  • Yao Y; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.
  • Kadam RU; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.
  • Lee CD; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.
  • Woehl JL; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.
  • Wu NC; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.
  • Zhu X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.
  • Kitamura S; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.
  • Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037; wilson@scripps.edu wolan@scripps.edu.
  • Wolan DW; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037.
Proc Natl Acad Sci U S A ; 117(31): 18431-18438, 2020 08 04.
Article en En | MEDLINE | ID: mdl-32690700
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antivirales / Evaluación Preclínica de Medicamentos / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Subtipo H5N1 del Virus de la Influenza A / Bibliotecas de Moléculas Pequeñas / Polarización de Fluorescencia Tipo de estudio: Evaluation_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Antivirales / Evaluación Preclínica de Medicamentos / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Subtipo H5N1 del Virus de la Influenza A / Bibliotecas de Moléculas Pequeñas / Polarización de Fluorescencia Tipo de estudio: Evaluation_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article