An insight into crystallization test: A neoteric approach for screening premalignant and malignant lesions.
J Cancer Res Ther
; 16(3): 440-444, 2020.
Article
en En
| MEDLINE
| ID: mdl-32719248
ABSTRACT
INTRODUCTION:
Crystallization test is based on the principle that, when a salt crystallizes out of an aqueous solution, the crystal growth is influenced by the presence of other substances in the solution, such as blood or plant extracts. If a mixture of copper chloride solution with a small amount of whole blood is allowed to crystallize under controlled experimental conditions, an aggregate of crystals forms. Crystallization method can be used as a diagnostic aid to provide information about the systemic conditions and general health of the patient.AIM:
This study aims to study the patterns of crystallization and to further determine the efficacy of crystallization test as a screening modality in premalignant lesions and oral squamous cell carcinoma (OSCC). MATERIALS ANDMETHODS:
Fifty patients of OSCC, 50 patients of premalignant lesions, and 50 healthy individuals were selected. One drop of blood was collected from the study groups to perform crystallization using cupric chloride. STATISTICAL ANALYSIS USED Statistical analysis was performed using Chi-square test, Student's t-test (two-tailed), and analysis of variance.RESULTS:
The different patterns of crystals formed were studied and statistically analyzed.CONCLUSION:
Based on the study, it was concluded that Crystallization test can be used as an effective screening modality for detection of premalignant lesions and OSCC.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Lesiones Precancerosas
/
Neoplasias de la Boca
/
Carcinoma de Células Escamosas
/
Biomarcadores de Tumor
/
Cobre
/
Cristalización
/
Leucoplasia
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Screening_studies
Idioma:
En
Revista:
J Cancer Res Ther
Año:
2020
Tipo del documento:
Article
País de afiliación:
India