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Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor.
Li, Qi; Xing, Shuaishuai; Chen, Ying; Liao, Qinghong; Xiong, Baichen; He, Siyu; Lu, Weixuan; Liu, Yang; Yang, Hongyu; Li, Qihang; Feng, Feng; Liu, Wenyuan; Chen, Yao; Sun, Haopeng.
Afiliación
  • Li Q; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Xing S; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Chen Y; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Liao Q; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Xiong B; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • He S; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, People's Republic of China.
  • Lu W; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Liu Y; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Yang H; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Li Q; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Feng F; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Liu W; Jiangsu Food and Pharmaceutical Science College, No. 4 Meicheng Road, Huai'an 223003, People's Republic of China.
  • Chen Y; School of Pharmacy, China Pharmaceutical University, Nanjing 211198, People's Republic of China.
  • Sun H; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China.
J Med Chem ; 63(17): 10030-10044, 2020 09 10.
Article en En | MEDLINE | ID: mdl-32787113
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Bencimidazoles / Butirilcolinesterasa / Inhibidores de la Colinesterasa / Fármacos Neuroprotectores / Aminoquinolinas Tipo de estudio: Guideline Idioma: En Revista: J Med Chem Año: 2020 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Bencimidazoles / Butirilcolinesterasa / Inhibidores de la Colinesterasa / Fármacos Neuroprotectores / Aminoquinolinas Tipo de estudio: Guideline Idioma: En Revista: J Med Chem Año: 2020 Tipo del documento: Article