Potential clinical use of azithromycin against gastroenteritis-causing pathogens other than Campylobacter.
New Microbiol
; 43(4): 198-200, 2020 Oct.
Article
en En
| MEDLINE
| ID: mdl-33021318
ABSTRACT
The activity of azithromycin against enteritis-producing agents other than Campylobacter spp. was studied. The susceptibility to azithromycin, through gradient test, of 88 clinical isolates (51 Salmonella spp., 23 Aeromonas spp., 10 Shigella sonnei and 4 Yersinia enterocolitica) for one year was studied prospectively. The results were compared with the activity of ampicillin, trimethoprim-sulfamethoxazole and ciprofloxacin by microdilution. For azithromycin, the minimum inhibitory concentration (MIC) 50 and MIC90 were 4 and 12 mg/l, respectively. Six (6.8%) isolates were simultaneously resistant to ampicillin, trimethoprim- sulfamethoxazole and ciprofloxacin, and 3 (50%) of them presented a MIC >256 mg/l. Azithromycin may be a good empirical therapeutic option for the treatment of bacterial enteritis.
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Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Plantas_medicinales
Asunto principal:
Azitromicina
/
Aeromonas
/
Enterobacteriaceae
/
Antibacterianos
Idioma:
En
Revista:
New Microbiol
Año:
2020
Tipo del documento:
Article