NMR-based Lavado cocoa chemical characterization and comparison with fermented cocoa varieties: Insights on cocoa's anti-amyloidogenic activity.

Ciaramelli, Carlotta; Palmioli, Alessandro; De Luigi, Ada; Colombo, Laura; Sala, Gessica; Salmona, Mario; Airoldi, Cristina

Ciaramelli, Carlotta; Palmioli, Alessandro; De Luigi, Ada; Colombo, Laura; Sala, Gessica; Salmona, Mario; Airoldi, Cristina.

Afiliación

Ciaramelli C; BioOrgNMR Lab, Department of Biotechnologies and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy; Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, P.zza dell'Ateneo Nuovo 1, 20126 Milano Italy. Electronic address: carlotta.ciaramelli@unimib.
Palmioli A; BioOrgNMR Lab, Department of Biotechnologies and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy; Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, P.zza dell'Ateneo Nuovo 1, 20126 Milano Italy. Electronic address: alessandro.palmioli@unimib.
De Luigi A; Department of Biochemistry and Molecular Pharmacology, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Via Mario Negri 2, 20156 Milano, Italy. Electronic address: ada.deluigi@marionegri.it.
Colombo L; Department of Biochemistry and Molecular Pharmacology, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Via Mario Negri 2, 20156 Milano, Italy. Electronic address: laura.colombo@marionegri.it.
Sala G; School of Medicine and Surgery, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, Italy; Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, P.zza dell'Ateneo Nuovo 1, 20126 Milano Italy. Electronic address: gessica.sala@unimib.it.
Salmona M; Department of Biochemistry and Molecular Pharmacology, Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS, Via Mario Negri 2, 20156 Milano, Italy. Electronic address: mario.salmona@marionegri.it.
Airoldi C; BioOrgNMR Lab, Department of Biotechnologies and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy; Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, P.zza dell'Ateneo Nuovo 1, 20126 Milano Italy. Electronic address: cristina.airoldi@unimib.it.

Food Chem ; 341(Pt 2): 128249, 2021 Mar 30.

Article en En | MEDLINE | ID: mdl-33038804

Asunto(s)

Cacao/química; Alimentos Fermentados/análisis; Péptidos beta-Amiloides/química; Péptidos beta-Amiloides/metabolismo; Antioxidantes/química; Cacao/metabolismo; Línea Celular Tumoral; Cromatografía Líquida de Alta Presión; Cromatografía de Fase Inversa; Flavanonas/análisis; Humanos; Espectroscopía de Resonancia Magnética; Fragmentos de Péptidos/química; Fragmentos de Péptidos/metabolismo; Extractos Vegetales/química; Extractos Vegetales/farmacología; Agregado de Proteínas/efectos de los fármacos; Teobromina/análisis

Palabras clave

Alzheimer's disease; Anti-amyloidogenic compounds; Aß peptides; Flavanols; Lavado cocoa; NMR spectroscopy

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cacao / Alimentos Fermentados Idioma: En Revista: Food Chem Año: 2021 Tipo del documento: Article