Zinc and SARS­CoV­2: A molecular modeling study of Zn interactions with RNA­dependent RNA­polymerase and 3C­like proteinase enzymes.

Pormohammad, Ali; Monych, Nadia K; Turner, Raymond J

Zinc and SARSCoV2: A molecular modeling study of Zn interactions with RNAdependent RNApolymerase and 3Clike proteinase enzymes.

Pormohammad, Ali; Monych, Nadia K; Turner, Raymond J.

Afiliación

Pormohammad A; Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N4V8, Canada.
Monych NK; Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N4V8, Canada.
Turner RJ; Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N4V8, Canada.

Int J Mol Med ; 47(1): 326-334, 2021 01.

Article en En | MEDLINE | ID: mdl-33236142

Asunto(s)

Proteasas 3C de Coronavirus/química; ARN Polimerasa Dependiente de ARN de Coronavirus/química; Modelos Moleculares; SARS-CoV-2/química; Zinc/química; Sitios de Unión; COVID-19/metabolismo; Proteasas 3C de Coronavirus/metabolismo; ARN Polimerasa Dependiente de ARN de Coronavirus/metabolismo; SARS-CoV-2/fisiología; Replicación Viral; Zinc/metabolismo

Palabras clave

coronavirus disease 2019; severe acute respiratory syndrome-coronavirus-2; zinc; coronovirus; RNA-dependent RNA-polymerase; 3Clike proteinase; enzyme inhibition; nutrition supplements; treatment; prevention

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Zinc / Modelos Moleculares / ARN Polimerasa Dependiente de ARN de Coronavirus / Proteasas 3C de Coronavirus / SARS-CoV-2 Tipo de estudio: Prognostic_studies Idioma: En Revista: Int J Mol Med Año: 2021 Tipo del documento: Article País de afiliación: Canadá

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