Prospective therapeutic potential of Tanshinone IIA: An updated overview.
Pharmacol Res
; 164: 105364, 2021 02.
Article
en En
| MEDLINE
| ID: mdl-33285229
ABSTRACT
In the past decades, the branch of complementary and alternative medicine based therapeutics has gained considerable attention worldwide. Pharmacological efficacy of various traditional medicinal plants, their products and/or product derivatives have been explored on an increasing scale. Tanshinone IIA (Tan IIA) is a pharmacologically active lipophilic component of Salvia miltiorrhiza extract. Tan IIA shares a history of high repute in Traditional Chinese Medicine. Reckoning with these, the present review collates the pharmacological properties of Tan IIA with a special emphasis on its therapeutic potential against diverse diseases including cardiovascular diseases, cerebrovascular diseases, cancer, diabetes, obesity and neurogenerative diseases. Further, possible applications of various therapeutic preparations of Tan IIA were discussed with special emphasis on nano-based drug delivery formulations. Considering the tremendous advancement in the field of nanomedicine and the therapeutic potential of Tan IIA, the convergence of these two aspects can be foreseen with great promise in clinical application.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapéuticos y Terapias MTCI:
Plantas_medicinales
Asunto principal:
Antiinflamatorios no Esteroideos
/
Abietanos
/
Antioxidantes
Tipo de estudio:
Risk_factors_studies
Idioma:
En
Revista:
Pharmacol Res
Año:
2021
Tipo del documento:
Article
País de afiliación:
Arabia Saudita