The Gut Microbiota and Traditional Chinese Medicine: A New Clinical Frontier on Cancer.
Curr Drug Targets
; 22(11): 1222-1231, 2021.
Article
en En
| MEDLINE
| ID: mdl-33845736
ABSTRACT
Gut microbiota is a complex microecosystem, which is called the second genome of the human body. Herbal medicine can balance tumor-suppressing bacteria and tumor-promoting bacteria and exert its anti-cancer effect by regulating gut microbiota. Traditional Chinese medicine (TCM) has a history of thousands of years in prevention and treatment of diseases in China. In recent decades, TCM has been shown to have an obvious advantage in prolonging the survival time and improving the living quality of patients with cancer. Notably, gut microbiota has become a new pathway to understanding TCM. In this review, we will focus on gut microbiota and tumor progression, especially the diversity, functionality and metabolites of gut microbiota affected by TCM in various cancer. We will also discuss the potential mechanism of gut microbiota for exploring TCM in anti-cancer effect. This article aims to comprehensively review the anti-cancer research of TCM by regulating gut microbiota, and address future perspectives and challenges of gut microbiota in TCM intervention for cancer.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Medicinas Tradicionales:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapéuticos y Terapias MTCI:
Terapias_biologicas
/
Plantas_medicinales
Asunto principal:
Plantas Medicinales
/
Medicamentos Herbarios Chinos
/
Microbioma Gastrointestinal
/
Neoplasias
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Curr Drug Targets
Año:
2021
Tipo del documento:
Article
País de afiliación:
China