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The efficacy of combined bright light and melatonin therapies on sleep and circadian outcomes: A systematic review.
Cheng, Daniel Chih Yung; Ganner, James L; Gordon, Christopher J; Phillips, Craig L; Grunstein, Ronald R; Comas, Maria.
Afiliación
  • Cheng DCY; Northern Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
  • Ganner JL; Northern Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
  • Gordon CJ; CIRUS, Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, NSW, Australia; Susan Wakil School of Nursing and Midwifery, Faculty of Medicine and Health, University of Sydney, NSW, Australia.
  • Phillips CL; Northern Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; CIRUS, Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, NSW, Australia; Department of Respiratory and Sleep Medicine, Royal North Shore Hospital, Sydney, Australia.
  • Grunstein RR; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; CIRUS, Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, NSW, Australia; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney Local Health Di
  • Comas M; Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; CIRUS, Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, NSW, Australia. Electronic address: comassoberats@gmail.com.
Sleep Med Rev ; 58: 101491, 2021 08.
Article en En | MEDLINE | ID: mdl-33962317
ABSTRACT
The aim of this systematic review was to investigate the effects of combined melatonin and bright light therapies on improved sleep and circadian outcomes. We conducted a systematic review that resulted in a total of eight papers meeting criteria. Four papers investigated the effectiveness of combined therapy in inducing a circadian phase shift on healthy participants. Combined therapy outperformed single light and melatonin therapies in phase advancing, but not in delaying, dim light melatonin onset (DLMO). The other four papers investigated the effect of combined therapy on sleep outcomes. Two of them were performed in elderly populations suffering from cognitive decline and two in delayed sleep-wake phase disorder (DSWPD) patients. While combined therapy was more beneficial than single therapy in elderly populations it did not show any benefit in DSWPD patients. The reported adverse effects of melatonin in elderly populations must be carefully considered. Future studies should investigate the separate and combined effect of melatonin and bright light on sleep and circadian outcomes in different target populations.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trastornos del Sueño-Vigilia / Trastornos del Sueño del Ritmo Circadiano / Melatonina Tipo de estudio: Systematic_reviews Idioma: En Revista: Sleep Med Rev Año: 2021 Tipo del documento: Article País de afiliación: Australia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Trastornos del Sueño-Vigilia / Trastornos del Sueño del Ritmo Circadiano / Melatonina Tipo de estudio: Systematic_reviews Idioma: En Revista: Sleep Med Rev Año: 2021 Tipo del documento: Article País de afiliación: Australia