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Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives.
Amporndanai, Kangsa; Meng, Xiaoli; Shang, Weijuan; Jin, Zhenmig; Rogers, Michael; Zhao, Yao; Rao, Zihe; Liu, Zhi-Jie; Yang, Haitao; Zhang, Leike; O'Neill, Paul M; Samar Hasnain, S.
Afiliación
  • Amporndanai K; Molecular Biophysics Group, Department of Biochemistry and System Biology, Institute of System, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, L69 7ZB, UK.
  • Meng X; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, L69 3BX, UK.
  • Shang W; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, Hubei, China.
  • Jin Z; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Rogers M; Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool, L69 7ZD, UK.
  • Zhao Y; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Rao Z; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Liu ZJ; iHuman Institute and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Yang H; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China. yanght@shanghaitech.edu.cn.
  • Zhang L; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, Hubei, China. zhangleike@wh.iov.cn.
  • O'Neill PM; Department of Chemistry, Faculty of Science and Engineering, University of Liverpool, Liverpool, L69 7ZD, UK. P.M.Oneill01@liverpool.ac.uk.
  • Samar Hasnain S; Molecular Biophysics Group, Department of Biochemistry and System Biology, Institute of System, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, L69 7ZB, UK. S.S.Hasnain@liverpool.ac.uk.
Nat Commun ; 12(1): 3061, 2021 05 24.
Article en En | MEDLINE | ID: mdl-34031399

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Azoles / Compuestos de Organoselenio / Proteasas 3C de Coronavirus / SARS-CoV-2 Idioma: En Revista: Nat Commun Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Azoles / Compuestos de Organoselenio / Proteasas 3C de Coronavirus / SARS-CoV-2 Idioma: En Revista: Nat Commun Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido