Investigating the causality of metabolites involved in one-carbon metabolism with the risk and age at onset of Parkinson's disease: A two-sample mendelian randomization study.

Zhao, Yating; Tian, Dandan; Guo, Na; Zhang, Chenguang; Zhu, Ruixia; Liu, Xu; Zhang, Jian

Zhao, Yating; Tian, Dandan; Guo, Na; Zhang, Chenguang; Zhu, Ruixia; Liu, Xu; Zhang, Jian.

Afiliación

Zhao Y; Department of Neurology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China.
Tian D; Department of Neurology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China.
Guo N; Department of Neurology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China.
Zhang C; Department of Neurology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China.
Zhu R; Department of Neurology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China.
Liu X; Department of Neurology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China. Electronic address: valentine1120@126.com.
Zhang J; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, China; Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China. Electronic address: jzhang@cmu.edu.cn.

Neurobiol Aging ; 108: 196-199, 2021 12.

Article en En | MEDLINE | ID: mdl-34325950

Asunto(s)

Ácido Fólico/genética; Ácido Fólico/metabolismo; Homocisteína/genética; Homocisteína/metabolismo; Análisis de la Aleatorización Mendeliana/métodos; Resultados Negativos; Enfermedad de Parkinson/etiología; Enfermedad de Parkinson/metabolismo; Vitamina B 12/genética; Vitamina B 12/metabolismo; Vitamina B 6/genética; Vitamina B 6/metabolismo; Edad de Inicio; Suplementos Dietéticos; Susceptibilidad a Enfermedades; Estudio de Asociación del Genoma Completo; Enfermedad de Parkinson/prevención & control; Riesgo

Palabras clave

Homocysteine; Mendelian randomization study; One-carbon metabolism; Parkinson's disease

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Vitamina B 12 / Vitamina B 6 / Análisis de la Aleatorización Mendeliana / Ácido Fólico / Resultados Negativos / Homocisteína Tipo de estudio: Clinical_trials / Etiology_studies / Risk_factors_studies Idioma: En Revista: Neurobiol Aging Año: 2021 Tipo del documento: Article País de afiliación: China

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