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Genetic insights into biological mechanisms governing human ovarian ageing.
Ruth, Katherine S; Day, Felix R; Hussain, Jazib; Martínez-Marchal, Ana; Aiken, Catherine E; Azad, Ajuna; Thompson, Deborah J; Knoblochova, Lucie; Abe, Hironori; Tarry-Adkins, Jane L; Gonzalez, Javier Martin; Fontanillas, Pierre; Claringbould, Annique; Bakker, Olivier B; Sulem, Patrick; Walters, Robin G; Terao, Chikashi; Turon, Sandra; Horikoshi, Momoko; Lin, Kuang; Onland-Moret, N Charlotte; Sankar, Aditya; Hertz, Emil Peter Thrane; Timshel, Pascal N; Shukla, Vallari; Borup, Rehannah; Olsen, Kristina W; Aguilera, Paula; Ferrer-Roda, Mònica; Huang, Yan; Stankovic, Stasa; Timmers, Paul R H J; Ahearn, Thomas U; Alizadeh, Behrooz Z; Naderi, Elnaz; Andrulis, Irene L; Arnold, Alice M; Aronson, Kristan J; Augustinsson, Annelie; Bandinelli, Stefania; Barbieri, Caterina M; Beaumont, Robin N; Becher, Heiko; Beckmann, Matthias W; Benonisdottir, Stefania; Bergmann, Sven; Bochud, Murielle; Boerwinkle, Eric; Bojesen, Stig E; Bolla, Manjeet K.
Afiliación
  • Ruth KS; Genetics of Human Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
  • Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
  • Hussain J; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Martínez-Marchal A; Genome Integrity and Instability Group, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.
  • Aiken CE; Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.
  • Azad A; University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
  • Thompson DJ; Department of Obstetrics and Gynaecology, University of Cambridge, The Rosie Hospital and NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • Knoblochova L; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Abe H; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Tarry-Adkins JL; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, Libechov, Czech Republic.
  • Gonzalez JM; Faculty of Science, Charles University, Prague, Czech Republic.
  • Fontanillas P; Division of Reproductive Sciences, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Claringbould A; University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
  • Bakker OB; Department of Obstetrics and Gynaecology, University of Cambridge, The Rosie Hospital and NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • Sulem P; Transgenic Core Facility, Department of Experimental Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Walters RG; 23andMe Inc., Sunnyvale, CA, USA.
  • Terao C; Structural and Computational Biology Unit, EMBL, Heidelberg, Germany.
  • Turon S; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.
  • Horikoshi M; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Onland-Moret NC; MRC Population Health Research Unit, University of Oxford, Oxford, UK.
  • Sankar A; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Hertz EPT; Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.
  • Timshel PN; Department of Applied Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
  • Shukla V; Transgenic Animal Unit, Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.
  • Borup R; Laboratory for Genomics of Diabetes and Metabolism, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Olsen KW; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
  • Aguilera P; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Ferrer-Roda M; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Huang Y; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Stankovic S; The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Timmers PRHJ; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Ahearn TU; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Alizadeh BZ; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Naderi E; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Andrulis IL; Reproductive Medicine, Department of Obstetrics and Gynaecology, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
  • Arnold AM; DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Aronson KJ; Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Consejo Superior de Investigaciones Científicas (CSIC) - Universidad de Sevilla -Universidad Pablo de Olavide, Seville, Spain.
  • Augustinsson A; Genome Integrity and Instability Group, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.
  • Bandinelli S; Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.
  • Barbieri CM; Genome Integrity and Instability Group, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.
  • Beaumont RN; Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.
  • Becher H; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
  • Beckmann MW; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.
  • Benonisdottir S; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
  • Bergmann S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
  • Bochud M; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Boerwinkle E; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Bojesen SE; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.
  • Bolla MK; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Nature ; 596(7872): 393-397, 2021 08.
Article en En | MEDLINE | ID: mdl-34349265
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Texto completo: 1 Asunto principal: Ovario / Envejecimiento Tipo de estudio: Prognostic_studies País/Región como asunto: Asia / Europa Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Asunto principal: Ovario / Envejecimiento Tipo de estudio: Prognostic_studies País/Región como asunto: Asia / Europa Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido