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Randomized, double-blind, placebo-controlled trial to examine the safety, pharmacokinetics and effects of Epimedium prenylflavonoids, on bone specific alkaline phosphatase and the osteoclast adaptor protein TRAF6 in post-menopausal women.
Yong, Eu-Leong; Cheong, Wei Fun; Huang, Zhongwei; Thu, Win Pa Pa; Cazenave-Gassiot, Amaury; Seng, Kok Yong; Logan, Susan.
Afiliación
  • Yong EL; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore. Electronic address: obgyel@nus.edu.sg.
  • Cheong WF; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore.
  • Huang Z; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore; Institute of Molecular and Cell Biology, Agency of Science, Technology and Research, 138673 Singapore.
  • Thu WPP; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore.
  • Cazenave-Gassiot A; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, 117456 Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 117596 Singapore.
  • Seng KY; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600 Singapore.
  • Logan S; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore.
Phytomedicine ; 91: 153680, 2021 Oct.
Article en En | MEDLINE | ID: mdl-34352588
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas Asunto principal: Flavonoides / Extractos Vegetales / Osteoporosis Posmenopáusica / Epimedium / Péptidos y Proteínas de Señalización Intracelular / Fosfatasa Alcalina Tipo de estudio: Clinical_trials Idioma: En Revista: Phytomedicine Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas Asunto principal: Flavonoides / Extractos Vegetales / Osteoporosis Posmenopáusica / Epimedium / Péptidos y Proteínas de Señalización Intracelular / Fosfatasa Alcalina Tipo de estudio: Clinical_trials Idioma: En Revista: Phytomedicine Año: 2021 Tipo del documento: Article