The Decursin Analog, CYJ-27, Suppresses Inflammation Via the Downregulation of NF-<i>&#954;</i>B and STAT-1.

Lee, Wonhwa; Sim, Hyunchae; Choi, Yoon-Jung; Seo, Ju Young; Yun, Mi-Young; Song, Gyu Yong; Bae, Jong-Sup

The Decursin Analog, CYJ-27, Suppresses Inflammation Via the Downregulation of NF-κB and STAT-1.

Lee, Wonhwa; Sim, Hyunchae; Choi, Yoon-Jung; Seo, Ju Young; Yun, Mi-Young; Song, Gyu Yong; Bae, Jong-Sup.

Afiliación

Lee W; College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Korea.
Sim H; Aging Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Choi YJ; College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Korea.
Seo JY; College of Pharmacy, Chungnam National University, Daejon, Korea.
Yun MY; College of Pharmacy, Chungnam National University, Daejon, Korea.
Song GY; Department of Beauty Science, Kwangju Women' University, Gwangju, South Korea.
Bae JS; College of Pharmacy, Chungnam National University, Daejon, Korea.

J Med Food ; 24(8): 852-859, 2021 Aug.

Article en En | MEDLINE | ID: mdl-34382871

Asunto(s)

Inflamación; FN-kappa B; Animales; Benzopiranos; Butiratos; Ciclooxigenasa 2/metabolismo; Regulación hacia Abajo; Hemo-Oxigenasa 1/genética; Hemo-Oxigenasa 1/metabolismo; Células Endoteliales de la Vena Umbilical Humana/metabolismo; Humanos; Inflamación/tratamiento farmacológico; Inflamación/genética; Lipopolisacáridos; Ratones; Factor 2 Relacionado con NF-E2/genética; Factor 2 Relacionado con NF-E2/metabolismo; FN-kappa B/genética; FN-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo II/genética; Óxido Nítrico Sintasa de Tipo II/metabolismo

Palabras clave

CYJ-27; endothelium; iNOS; p-STAT-1

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: FN-kappa B / Inflamación Idioma: En Revista: J Med Food Año: 2021 Tipo del documento: Article