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BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies.
Berger, Markus; Wortmann, Lars; Buchgraber, Philipp; Lücking, Ulrich; Zitzmann-Kolbe, Sabine; Wengner, Antje M; Bader, Benjamin; Bömer, Ulf; Briem, Hans; Eis, Knut; Rehwinkel, Hartmut; Bartels, Florian; Moosmayer, Dieter; Eberspächer, Uwe; Lienau, Philip; Hammer, Stefanie; Schatz, Christoph A; Wang, Qiuwen; Wang, Qi; Mumberg, Dominik; Nising, Carl F; Siemeister, Gerhard.
Afiliación
  • Berger M; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Wortmann L; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Buchgraber P; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Lücking U; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Zitzmann-Kolbe S; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Wengner AM; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Bader B; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Bömer U; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Briem H; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Eis K; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Rehwinkel H; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Bartels F; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Moosmayer D; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Eberspächer U; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Lienau P; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Hammer S; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Schatz CA; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Wang Q; Pharmaron Beijing Co., Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China.
  • Wang Q; WuXi AppTec (Wuhan) Co., Ltd., 666 Gaoxin Road, East Lake High-tech Development Zone, Wuhan 430075, P. R. China.
  • Mumberg D; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Nising CF; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
  • Siemeister G; Research & Development, Pharmaceuticals, Bayer AG, Berlin 13353, Germany.
J Med Chem ; 64(17): 12723-12737, 2021 09 09.
Article en En | MEDLINE | ID: mdl-34428039
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia Asunto principal: Regulación de la Expresión Génica / Proteína Quinasa Activada por ADN / Antineoplásicos Idioma: En Revista: J Med Chem Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia Asunto principal: Regulación de la Expresión Génica / Proteína Quinasa Activada por ADN / Antineoplásicos Idioma: En Revista: J Med Chem Año: 2021 Tipo del documento: Article País de afiliación: Alemania