Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF-<i>&#954;</i>B Suppression and NLRP3 Inflammasome Inhibition.

Ran, Yuanyuan; Su, Wei; Gao, Fuhai; Ding, Zitong; Yang, Shuiqing; Ye, Lin; Chen, Xuechai; Tian, Guiqin; Xi, Jianing; Liu, Zongjian

Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF-κB Suppression and NLRP3 Inflammasome Inhibition.

Ran, Yuanyuan; Su, Wei; Gao, Fuhai; Ding, Zitong; Yang, Shuiqing; Ye, Lin; Chen, Xuechai; Tian, Guiqin; Xi, Jianing; Liu, Zongjian.

Afiliación

Ran Y; Department of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang, Badachu Road, Shijingshan District, Beijing 100144, China.
Su W; Department of Neurosurgery, Beijing Tsinghua Chang Gung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China.
Gao F; Department of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang, Badachu Road, Shijingshan District, Beijing 100144, China.
Ding Z; Department of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang, Badachu Road, Shijingshan District, Beijing 100144, China.
Yang S; Department of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang, Badachu Road, Shijingshan District, Beijing 100144, China.
Ye L; School of Materials Science and Engineering, Beijing Institute of Technology, No. 5 Zhongguancun South Road, Haidian District, Beijing 100081, China.
Chen X; College of Life Science and Bioengineering, Beijing University of Technology, 100 Ping Le Yuan, Chaoyang District, Beijing 100124, China.
Tian G; Department of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang, Badachu Road, Shijingshan District, Beijing 100144, China.
Xi J; Department of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang, Badachu Road, Shijingshan District, Beijing 100144, China.
Liu Z; Department of Rehabilitation, Beijing Rehabilitation Hospital, Capital Medical University, Xixiazhuang, Badachu Road, Shijingshan District, Beijing 100144, China.

Oxid Med Cell Longev ; 2021: 1552127, 2021.

Article en En | MEDLINE | ID: mdl-34630845

Asunto(s)

Isquemia Encefálica/tratamiento farmacológico; Isquemia Encefálica/metabolismo; Curcuma/química; Curcumina/administración & dosificación; Inflamasomas/metabolismo; Accidente Cerebrovascular Isquémico/tratamiento farmacológico; Accidente Cerebrovascular Isquémico/metabolismo; Macrófagos/metabolismo; Microglía/metabolismo; FN-kappa B/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Fitoterapia/métodos; Extractos Vegetales/administración & dosificación; Piroptosis/efectos de los fármacos; Transducción de Señal/efectos de los fármacos; Sustancia Blanca/efectos de los fármacos; Sustancia Blanca/lesiones; Animales; Células Cultivadas; Modelos Animales de Enfermedad; Masculino; Ratones; Ratones Endogámicos C57BL; Proteína con Dominio Pirina 3 de la Familia NLR/genética; Piroptosis/genética; Transducción de Señal/genética; Transfección; Resultado del Tratamiento

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia / Plantas_medicinales Asunto principal: Extractos Vegetales / Transducción de Señal / Isquemia Encefálica / FN-kappa B / Microglía / Curcumina / Curcuma / Inflamasomas / Sustancia Blanca / Piroptosis Tipo de estudio: Prognostic_studies Idioma: En Revista: Oxid Med Cell Longev Año: 2021 Tipo del documento: Article País de afiliación: China

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google