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The use of GRADE approach in Cochrane reviews of TCM was insufficient: a cross-sectional survey.
Wang, Qi; Xiao, Ya; Guo, Taotao; Zhu, Hongfei; Li, Jieyun; Lai, Honghao; Zhang, Ying; Yang, Fengwen; Liu, Yu; Yang, Kehu; Chen, Yaolong; Tian, Jinhui; Ding, Guowu; Ge, Long.
Afiliación
  • Wang Q; Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou, China.
  • Xiao Y; Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou, China.
  • Guo T; Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou, China.
  • Zhu H; Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou, China.
  • Li J; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
  • Lai H; Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou, China.
  • Zhang Y; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
  • Yang F; Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
  • Liu Y; Department of Scientific Research Management, China Academy of Chinese Medical Sciences, Beijing, China; China Center for Evidence Based Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China; Acupuncture Department, Guang' anmen Hospital, China Academy of Chinese Me
  • Yang K; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, China.
  • Chen Y; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Chinese GRADE Center, Lanzhou, China.
  • Tian J; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, China. Electronic address: tjh996@163.com.
  • Ding G; Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou, China. Electronic address: dinggw@lzu.edu.cn.
  • Ge L; Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China; Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou, China; Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Pr
J Clin Epidemiol ; 142: 1-9, 2022 02.
Article en En | MEDLINE | ID: mdl-34752940
ABSTRACT

OBJECTIVE:

To conduct a cross-sectional survey on the application status of the Grades of Recommendations Assessment Development and Evaluation (GRADE) in Cochrane systematic reviews (CSRs) of traditional Chinese medicine (TCM). STUDY DESIGN AND

SETTING:

We searched CSRs of TCM from the inception to December 2020 in the Cochrane Library database. General characteristics and details of GRADE were extracted.

RESULTS:

Among 226 CSRs of TCM, 86 (38.05%) involving 711 outcomes used GRADE to rate the certainty of evidence. Topics mainly focused on genitourinary diseases (17.44%), diseases of the musculoskeletal system or connective tissue (11.63%), and diseases of the nervous system (10.47%). Only 15.89% of the outcomes reported high or moderate certainty of evidence. Acupuncture was the most common intervention. There were no significant differences in evidence certainty between acupuncture and non-acupuncture, between TCM alone and integrated Chinese and western medicine, or between Chinese patent medicines and non-Chinese patent medicines (P > 0.05). Among 1 273 instances of downgrading, 44.62% were due to the risk of bias and 40.14% due to imprecision.

CONCLUSION:

Overall, GRADE approach is not widely used in CSRs of TCM. The certainty of evidence is generally low to very low, mainly because of the serious risk of bias and imprecision.
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapéuticos y Terapias MTCI: Terapias_manuales Asunto principal: Terapia por Acupuntura / Medicina Tradicional China Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Idioma: En Revista: J Clin Epidemiol Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapéuticos y Terapias MTCI: Terapias_manuales Asunto principal: Terapia por Acupuntura / Medicina Tradicional China Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Idioma: En Revista: J Clin Epidemiol Año: 2022 Tipo del documento: Article País de afiliación: China