Berberine and lycopene as alternative or add-on therapy to metformin and statins, a review.
Eur J Pharmacol
; 913: 174590, 2021 Dec 15.
Article
en En
| MEDLINE
| ID: mdl-34801530
ABSTRACT
Nutraceuticals are principally extracted from natural products that are frequently safe and well-tolerated. Lycopene and berberine are natural plants with a wide range of beneficial effects including protective activities against metabolic disorders such as diabetes and cardiovascular diseases. These compounds might be considered technically more as a drug than a nutraceutical and could be prescribed as a product. However, further studies are needed to understand if these supplements could affect metabolic syndrome outcomes. Even if nutraceuticals exert a prophylactic activity within the body, their bioactivity and bioavailability have high interindividual variation, and precise assessment of biological function of these bioactive compounds in randomized clinical trials is critical. However, these reports must be interpreted with more considerations due to the low quality of the trials. The aim of this paper is to bring evidence about the management of cardiovascular diseases and diabetes through the use of nutraceuticals with particular attention to lycopene and berberine effectiveness.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Métodos Terapéuticos y Terapias MTCI:
Plantas_medicinales
Asunto principal:
Berberina
/
Enfermedades Cardiovasculares
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Suplementos Dietéticos
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Diabetes Mellitus
/
Licopeno
Tipo de estudio:
Clinical_trials
Idioma:
En
Revista:
Eur J Pharmacol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Irán