Novel pectin-like polysaccharide from Panax notoginseng attenuates renal tubular cells fibrogenesis induced by TGF-ß.

Huang, Chunfan; Jing, Xiaoqi; Wu, Qianhu; Ding, Kan

Huang, Chunfan; Jing, Xiaoqi; Wu, Qianhu; Ding, Kan.

Afiliación

Huang C; College of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Nanjing, Jiangsu Province 210029, China; Glycochemistry and Glycobiology Lab, Carbohydrate-based Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 2
Jing X; Glycochemistry and Glycobiology Lab, Carbohydrate-based Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China; Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Med
Wu Q; College of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Nanjing, Jiangsu Province 210029, China; Zhenjiang the Third People's Hospital, 300 Daijiamen Avenue, Zhenjiang, Jiangsu Province 212021, China. Electronic address: jszjsyjgb@163.com.
Ding K; College of Pharmacy, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Nanjing, Jiangsu Province 210029, China; Glycochemistry and Glycobiology Lab, Carbohydrate-based Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 2

Carbohydr Polym ; 276: 118772, 2022 Jan 15.

Article en En | MEDLINE | ID: mdl-34823789

Asunto(s)

Enfermedades Renales/metabolismo; Túbulos Renales/metabolismo; Panax notoginseng/química; Pectinas/farmacología; Factor de Crecimiento Transformador beta/metabolismo; Actinas/metabolismo; Cadherinas/metabolismo; Línea Celular; Células Epiteliales/metabolismo; Transición Epitelial-Mesenquimal/efectos de los fármacos; Fibronectinas/metabolismo; Fibrosis/metabolismo; Humanos; Riñón/metabolismo; Riñón/patología; Pectinas/análisis; Pectinas/química; Vimentina/metabolismo

Palabras clave

Epithelial-mesenchymal transition; Panax notoginseng; Pectin; Polysaccharide; Renal fibrosis

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factor de Crecimiento Transformador beta / Pectinas / Panax notoginseng / Enfermedades Renales / Túbulos Renales Idioma: En Revista: Carbohydr Polym Año: 2022 Tipo del documento: Article

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