Chemical constituents and biological activities of Artemisia argyi H.Lév. & vaniot.
Nat Prod Res
; 37(8): 1401-1405, 2023 Apr.
Article
en En
| MEDLINE
| ID: mdl-34847785
ABSTRACT
Artemisia argyi is a widely distributed and inexpensive plant resource, and study on its chemical compositions and biological activities will provide an important basis for its food applications and pharmaceutical developments. In this study, fourteen known guaiane-type sesquiterpenes (1-14), four known eudesmane-type sesquiterpenes (15-18), two known germacranolide-type sesquiterpenes (19, 20), and eight other types of terpenoids (20-28) were isolated from the leaves of A. argyi by polyamide and ODS CC and HPLC. The structures of all compounds are determined by 1 D NMR (1H-NMRã13C-NMR) and literature comparison. Among them, compounds 1 and 8 were isolated from Chinese folk medicine A. argyi for the first time. Besides, the LPS-induced RAW264.7 cell model has been evaluated the anti-inflammatory activities in vitro by the Griess reagent. The results indicated that the guaianolide sesquiterpenoids obtained from A. argyi have an excellent ability to inhibit NO production, especially Argyin A, a guaianolide sesquiterpenoid with isovaleryloxy substitution.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Sesquiterpenos
/
Artemisia
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Nat Prod Res
Año:
2023
Tipo del documento:
Article