Curcumin, novel application in reversing myocardial fibrosis in the treatment for atrial fibrillation from the perspective of transcriptomics in rat model.

Yue, Honghua; Zhao, Xueshan; Liang, Weitao; Qin, Xiaoli; Bian, Longrong; He, Kang; Wu, Zhong

Yue, Honghua; Zhao, Xueshan; Liang, Weitao; Qin, Xiaoli; Bian, Longrong; He, Kang; Wu, Zhong.

Afiliación

Yue H; Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Zhao X; Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Liang W; Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Qin X; Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Bian L; Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
He K; Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Wu Z; Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China. Electronic address: wuzhong71@163.com.

Biomed Pharmacother ; 146: 112522, 2022 Feb.

Article en En | MEDLINE | ID: mdl-34894517

Asunto(s)

Fibrilación Atrial; Curcumina; Miocardio; Transcriptoma; Animales; Fibrilación Atrial/tratamiento farmacológico; Fibrilación Atrial/genética; Fibrilación Atrial/patología; Curcumina/farmacología; Curcumina/uso terapéutico; Modelos Animales de Enfermedad; Fibrosis; Atrios Cardíacos/patología; Miocardio/patología; Ratas; Ratas Sprague-Dawley; Transcriptoma/efectos de los fármacos; Factor de Crecimiento Transformador beta1/genética

Palabras clave

Atrial fibrillation; Curcumin; Myocardial fibrosis; Transcriptome analysis

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Texto completo: 1 Bases de datos: MEDLINE Métodos Terapéuticos y Terapias MTCI: Terapias_biologicas / Aromoterapia / Plantas_medicinales Asunto principal: Fibrilación Atrial / Curcumina / Transcriptoma / Miocardio Tipo de estudio: Prognostic_studies Idioma: En Revista: Biomed Pharmacother Año: 2022 Tipo del documento: Article País de afiliación: China

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