[Protective effect of ginsenoside Rg_1 aganist diabetic retinopathy by inhibiting NLRP3 inflammasome in type 2 diabetic mice].

Li, Bin; Zhang, Da-Chuan; Li, Xue-Wang; Dong, Xia-Nan; Li, Wei-Ping; Li, Wei-Zu

Li, Bin; Zhang, Da-Chuan; Li, Xue-Wang; Dong, Xia-Nan; Li, Wei-Ping; Li, Wei-Zu.

Afiliación

Li B; Department of Ophthalmology, the Third People's Hospital of Hefei Hefei 230022, China.
Zhang DC; Department of Ophthalmology, the Third People's Hospital of Hefei Hefei 230022, China.
Li XW; Department of Pharmacology/Key Laboratory of Anti-inflammatory and Immunopharmacology, Ministry of Education/Pharmacology 3rd Grade Laboratory of State Administration of Traditional Chinese Medicine, Anhui Medical University Hefei 230032, China.
Dong XN; Department of Pharmacology/Key Laboratory of Anti-inflammatory and Immunopharmacology, Ministry of Education/Pharmacology 3rd Grade Laboratory of State Administration of Traditional Chinese Medicine, Anhui Medical University Hefei 230032, China.
Li WP; Department of Pharmacology/Key Laboratory of Anti-inflammatory and Immunopharmacology, Ministry of Education/Pharmacology 3rd Grade Laboratory of State Administration of Traditional Chinese Medicine, Anhui Medical University Hefei 230032, China.
Li WZ; Department of Pharmacology/Key Laboratory of Anti-inflammatory and Immunopharmacology, Ministry of Education/Pharmacology 3rd Grade Laboratory of State Administration of Traditional Chinese Medicine, Anhui Medical University Hefei 230032, China.

Zhongguo Zhong Yao Za Zhi ; 47(2): 476-483, 2022 Jan.

Article en Zh | MEDLINE | ID: mdl-35178992

Asunto(s)

Diabetes Mellitus Experimental; Diabetes Mellitus Tipo 2; Retinopatía Diabética; Ginsenósidos; Anciano; Animales; Diabetes Mellitus Experimental/tratamiento farmacológico; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Tipo 2/complicaciones; Diabetes Mellitus Tipo 2/tratamiento farmacológico; Diabetes Mellitus Tipo 2/genética; Retinopatía Diabética/tratamiento farmacológico; Retinopatía Diabética/genética; Ginsenósidos/farmacología; Humanos; Inflamasomas/metabolismo; Ratones; Persona de Mediana Edad; FN-kappa B/genética; FN-kappa B/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/genética; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Transducción de Señal; Factor A de Crecimiento Endotelial Vascular/genética

Palabras clave

NLRP3 inflammasome; diabetic retinopathy; ginsenoside Rg_1; vascular transforming growth factor

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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Ginsenósidos / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Retinopatía Diabética Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Año: 2022 Tipo del documento: Article País de afiliación: China

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