Cytotoxic sesquiterpene lactones and lignans from Cousinia turkmenorum Bornm (Asteraceae).
Nat Prod Res
; 36(23): 6096-6100, 2022 Dec.
Article
en En
| MEDLINE
| ID: mdl-35227157
ABSTRACT
Seven sesquiterpene lactones, chlorophyssopifolin E (1), aguerin B (2), repdiolide triol (3), solistitiolide (4), aitchisonolide (5), sinicin B (6), cynaropicrin (7), along with four lignans arctigenin (8), arctiin (9), matairesinol (10), and matairesinoside (11) were isolated for the first time from the aerial parts of Cousinia turkmenorum Bornm. Among the isolated compounds, aguerin B (2) showed the most cytotoxic activity against MCF7 cell lines with IC50 value of 18.9 µM. Findings of this study could be useful for the development of new anticancer agents from nature.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Sesquiterpenos
/
Lignanos
/
Asteraceae
/
Antineoplásicos
/
Antineoplásicos Fitogénicos
Idioma:
En
Revista:
Nat Prod Res
Año:
2022
Tipo del documento:
Article
País de afiliación:
Irán