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An integrated network pharmacology and cell metabolomics approach to reveal the role of rhein, a novel PPARα agonist, against renal fibrosis by activating the PPARα-CPT1A axis.
Xiao, Qiming; Yu, Xixi; Yu, Xinwei; Liu, Shundi; Jiang, Jianping; Cheng, Yu; Lin, Hao; Wang, Yuzhen; Zhang, Xiaoshan; Ye, Xiaoxia; Xiang, Zheng.
Afiliación
  • Xiao Q; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Yu X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Yu X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Liu S; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Jiang J; Medical School, Zhejiang University City College, Hangzhou, 310015, China.
  • Cheng Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Lin H; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Wang Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Zhang X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
  • Ye X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. Electronic address: yxx@wmu.edu.cn.
  • Xiang Z; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China; Medical School, Zhejiang University City College, Hangzhou, 310015, China. Electronic address: Xiangz@zucc.edu.cn.
Phytomedicine ; 102: 154147, 2022 Jul 20.
Article en En | MEDLINE | ID: mdl-35567992
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: PPAR alfa / Enfermedades Renales Tipo de estudio: Prognostic_studies Idioma: En Revista: Phytomedicine Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
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PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: PPAR alfa / Enfermedades Renales Tipo de estudio: Prognostic_studies Idioma: En Revista: Phytomedicine Año: 2022 Tipo del documento: Article País de afiliación: China