Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.

Xie, Chun-Feng; Feng, Kun-Liang; Wang, Ji-Nan; Luo, Rui; Fang, Chong-Kai; Zhang, Ying; Shen, Chuang-Peng; Zhong, Chong

Xie, Chun-Feng; Feng, Kun-Liang; Wang, Ji-Nan; Luo, Rui; Fang, Chong-Kai; Zhang, Ying; Shen, Chuang-Peng; Zhong, Chong.

Afiliación

Xie CF; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; Department of General Surgery, Liuzhou Traditional Chinese Medical Hospital, 545001, Liuzhou, China.
Feng KL; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Wang JN; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Luo R; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Fang CK; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Zhang Y; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Shen CP; Department of Endocrinology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. Electronic address: shenchuangpeng@gzucm.edu.cn.
Zhong C; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. Electronic address: zhongchong1732@gzucm.edu.cn.

J Ethnopharmacol ; 294: 115360, 2022 Aug 10.

Article en En | MEDLINE | ID: mdl-35568116

Asunto(s)

Carcinoma Hepatocelular; Neoplasias Hepáticas; MicroARNs; Animales; Carcinoma Hepatocelular/tratamiento farmacológico; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Línea Celular Tumoral; Movimiento Celular; Proliferación Celular; Cromatografía Liquida; Transición Epitelial-Mesenquimal; Regulación Neoplásica de la Expresión Génica; Humanos; Neoplasias Hepáticas/tratamiento farmacológico; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Ratones; Ratones Desnudos; MicroARNs/genética; MicroARNs/metabolismo; Transducción de Señal; Espectrometría de Masas en Tándem; Microambiente Tumoral

Palabras clave

Epithelial mesenchymal transition; Exosome; Hepatocellular carcinoma; Jianpi huayu decoction; miR-23a-3p

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / MicroARNs / Neoplasias Hepáticas Idioma: En Revista: J Ethnopharmacol Año: 2022 Tipo del documento: Article País de afiliación: China

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