A saponin from astragalus promotes pancreatic ductal organoids differentiation into insulin-producing cells.

Yu, Wen; Wang, Yannan; Jiang, Di; Shang, Jie; Liu, Miao; Efferth, Thomas; Teng, Chun-Bo

Yu, Wen; Wang, Yannan; Jiang, Di; Shang, Jie; Liu, Miao; Efferth, Thomas; Teng, Chun-Bo.

Afiliación

Yu W; College of Life Science, Northeast Forestry University, Harbin, PR China.
Wang Y; College of Life Science, Northeast Forestry University, Harbin, PR China.
Jiang D; College of Life Science, Northeast Forestry University, Harbin, PR China.
Shang J; College of Life Science, Northeast Forestry University, Harbin, PR China.
Liu M; College of Life Science, Northeast Forestry University, Harbin, PR China.
Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Teng CB; College of Life Science, Northeast Forestry University, Harbin, PR China. Electronic address: chunboteng@nefu.edu.cn.

Phytomedicine ; 102: 154190, 2022 Jul 20.

Article en En | MEDLINE | ID: mdl-35636173

Asunto(s)

Diabetes Mellitus Tipo 2; Células Secretoras de Insulina; Saponinas; Animales; Péptido C/metabolismo; Diferenciación Celular/fisiología; Diabetes Mellitus Tipo 2/metabolismo; Insulina/metabolismo; Células Secretoras de Insulina/metabolismo; Ratones; Organoides/metabolismo; Saponinas/metabolismo; Saponinas/farmacología

Palabras clave

Astragalus saponins; Diabetes mellitus; Differentiation; Insulin-producing cells; Organoids

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Saponinas / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina Idioma: En Revista: Phytomedicine Año: 2022 Tipo del documento: Article

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