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Emodin-induced hepatotoxicity is enhanced by 3-methylcholanthrene through activating aryl hydrocarbon receptor and inducing CYP1A1 in vitro and in vivo.
Wang, Meixi; Zhang, Zuqi; Ruan, Panpan; Zhang, Guangchen; Xiao, Chengrong; Wang, Yuguang; Gao, Yue.
Afiliación
  • Wang M; Guangdong Pharmaceutical University, Guangzhou, 510006, PR China; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050,
  • Zhang Z; Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, PR China; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.
  • Ruan P; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.
  • Zhang G; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.
  • Xiao C; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.
  • Wang Y; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China. Electronic address: wangyg@bmi.ac.cn.
  • Gao Y; Guangdong Pharmaceutical University, Guangzhou, 510006, PR China; Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, PR China; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China. Electronic address: gaoyue@bmi.ac.cn.
Chem Biol Interact ; 365: 110089, 2022 Sep 25.
Article en En | MEDLINE | ID: mdl-35934134
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Emodina / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article
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Texto completo: 1 Bases de datos: MEDLINE Medicinas Tradicionales: Medicinas_tradicionales_de_asia / Medicina_china Asunto principal: Emodina / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article