Anti-depressant-like effect of fermented Gastrodia elata Bl. by regulating monoamine levels and BDNF/NMDAR pathways in mice.

Gao, Ming; Wu, Yi; Yang, Lishou; Chen, Faju; Li, Liangqun; Li, Qiji; Wang, Yu; Li, Lilang; Peng, Mei; Yan, Yanfang; Yang, Juan; Yang, Xiaosheng

Gao, Ming; Wu, Yi; Yang, Lishou; Chen, Faju; Li, Liangqun; Li, Qiji; Wang, Yu; Li, Lilang; Peng, Mei; Yan, Yanfang; Yang, Juan; Yang, Xiaosheng.

Afiliación

Gao M; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Wu Y; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Yang L; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Chen F; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Li L; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Li Q; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Wang Y; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Li L; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Peng M; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Yan Y; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Yang J; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China.
Yang X; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, 550014, PR China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, 550014, PR China. Electronic address: gzcnp@sina.cn.

J Ethnopharmacol ; 301: 115832, 2023 Jan 30.

Article en En | MEDLINE | ID: mdl-36283636

Asunto(s)

Gastrodia; Animales; Ratones; Antidepresivos/farmacología; Antidepresivos/uso terapéutico; Conducta Animal; Factor Neurotrófico Derivado del Encéfalo; Depresión/tratamiento farmacológico; Depresión/metabolismo; Modelos Animales de Enfermedad; Dopamina/metabolismo; Gastrodia/química; Monoaminooxidasa/metabolismo; N-Metilaspartato; Extractos Vegetales/farmacología; Extractos Vegetales/uso terapéutico; Extractos Vegetales/química; Propano/farmacología; Serotonina/metabolismo; Estrés Psicológico/tratamiento farmacológico; Receptores de N-Metil-D-Aspartato/metabolismo

Palabras clave

Anti-depression; Fermentation; Gastrodia elata Bl.; Monoamine; Signaling pathway

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Gastrodia Idioma: En Revista: J Ethnopharmacol Año: 2023 Tipo del documento: Article