Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis.

Yoshida, Mio; Ishihara, Tomoaki; Isobe, Yosuke; Arita, Makoto

Yoshida, Mio; Ishihara, Tomoaki; Isobe, Yosuke; Arita, Makoto.

Afiliación

Yoshida M; Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Ishihara T; Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Isobe Y; Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Arita M; Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.

FASEB J ; 36(12): e22648, 2022 12.

Article en En | MEDLINE | ID: mdl-36374250

Asunto(s)

Familia 4 del Citocromo P450; Dermatitis; Ácidos Grasos Omega-3; Psoriasis; Animales; Ratones; Dermatitis/genética; Dermatitis/metabolismo; Ácidos Docosahexaenoicos/metabolismo; Ácido Eicosapentaenoico/metabolismo; Ácidos Grasos Omega-3/metabolismo; Interleucina-23; Lipopolisacáridos/toxicidad; Psoriasis/genética; Psoriasis/metabolismo; Familia 4 del Citocromo P450/genética

Palabras clave

dendritic cell; fatty acid metabolism; lipid mediator; n-3 polyunsaturated fatty acids; psoriasis

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Psoriasis / Ácidos Grasos Omega-3 / Dermatitis / Familia 4 del Citocromo P450 Idioma: En Revista: FASEB J Año: 2022 Tipo del documento: Article País de afiliación: Japón

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