Natural and Pseudonatural Lindenane Heterodimers from Sarcandra glabra by Molecular Networking.
Org Lett
; 24(49): 9107-9111, 2022 12 16.
Article
en En
| MEDLINE
| ID: mdl-36469558
Sarglaoxolane A (1), the first lindenane-normonoterpene heterodimer fused by tetrahydrofuran, was discovered in Sarcandra glabra guided by the first proposed single-node-based molecular networking approach. Moreover, two pseudonatural derivatives (2 and 3) with an oxa-difuranofurone moiety were transformed from 1 and confirmed by X-ray diffraction, and also proven to exist in the plant extract. A combination of molecular networking and biomimetic transformation can significantly promote the discovery and structural elucidation of novel natural products.
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Bases de datos:
MEDLINE
Asunto principal:
Magnoliopsida
Idioma:
En
Revista:
Org Lett
Año:
2022
Tipo del documento:
Article
País de afiliación:
China