Association between high-dose methotrexate-induced toxicity and polymorphisms within methotrexate pathway genes in acute lymphoblastic leukemia.

Xu, Meng; Wu, Shuangshuang; Wang, Yue; Zhao, Yundong; Wang, Ximin; Wei, Changhong; Liu, Xueying; Hao, Feng; Hu, Cheng

Xu, Meng; Wu, Shuangshuang; Wang, Yue; Zhao, Yundong; Wang, Ximin; Wei, Changhong; Liu, Xueying; Hao, Feng; Hu, Cheng.

Afiliación

Xu M; College of Laboratory Medicine, Jilin Medical University, Jilin, China.
Wu S; School of Laboratory Medicine, Beihua University, Jilin, China.
Wang Y; Department of Pediatric Hematology, The First Hospital of Jilin University, Changchun, China.
Zhao Y; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, China.
Wang X; Department of Pediatric Hematology, The First Hospital of Jilin University, Changchun, China.
Wei C; School of Laboratory Medicine, Beihua University, Jilin, China.
Liu X; Jilin Drug Inspection Center, Changchun, China.
Hao F; Department of Hematology, The Linyi Central Hospital, Linyi, China.
Hu C; College of Laboratory Medicine, Jilin Medical University, Jilin, China.

Front Pharmacol ; 13: 1003812, 2022.

Article en En | MEDLINE | ID: mdl-36532750

Palabras clave

acute lymphoblastic leukemia; gene polymorphisms; high-dose methotrexate; mutation; toxicity

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China

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