A Self-Emulsified Adjuvant System Containing the Immune Potentiator Alpha Tocopherol Induces Higher Neutralizing Antibody Responses than a Squalene-Only Emulsion When Evaluated with a Recombinant Cytomegalovirus (CMV) Pentamer Antigen in Mice.

Lodaya, Rushit N; Kanitkar, Amey P; Ashraf, Asma; Bamba, Douty; Amiji, Mansoor M; O'Hagan, Derek T

Lodaya, Rushit N; Kanitkar, Amey P; Ashraf, Asma; Bamba, Douty; Amiji, Mansoor M; O'Hagan, Derek T.

Afiliación

Lodaya RN; Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA 02115, USA.
Kanitkar AP; GSK, Rockville Centre for Vaccines Research, Rockville, MD 20850, USA.
Ashraf A; GSK, Rockville Centre for Vaccines Research, Rockville, MD 20850, USA.
Bamba D; GSK, Rockville Centre for Vaccines Research, Rockville, MD 20850, USA.
Amiji MM; GSK, Rockville Centre for Vaccines Research, Rockville, MD 20850, USA.
O'Hagan DT; Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA 02115, USA.

Pharmaceutics ; 15(1)2023 Jan 10.

Article en En | MEDLINE | ID: mdl-36678865

Palabras clave

adjuvants; alpha-tocopherol; nanoemulsions; self-emulsification; vaccine delivery

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos